Optimization of an in vitro assay methodology for competitive binding of thyroidogenic xenobiotics with thyroxine on human transthyretin and albumin

Thyroid hormones (THs) are involved in the regulation of many physiological processes in vertebrates. Competition for TH binding sites on serum transport proteins can interfere with delivery of THs to target tissues, and this is a potential mechanism of action of exogenous thyroidogenic substances....

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Detalles Bibliográficos
Autores principales: Hill, Katie L., Hamers, Timo, Kamstra, Jorke H., Willmore, William G., Letcher, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671392/
https://www.ncbi.nlm.nih.gov/pubmed/29124017
http://dx.doi.org/10.1016/j.mex.2017.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671392/
https://www.ncbi.nlm.nih.gov/pubmed/29124017
http://dx.doi.org/10.1016/j.mex.2017.10.004

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