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NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice

Sterile lung injury is an important clinical problem that complicates the course of severely ill patients. Interruption of blood flow, namely ischemia–reperfusion (IR), initiates a sterile inflammatory response in the lung that is believed to be maladaptive. The rationale for this study was to eluci...

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Detalles Bibliográficos
Autores principales: Tian, Xiaoli, Sun, He, Casbon, Amy-Jo, Lim, Edward, Francis, Kevin P., Hellman, Judith, Prakash, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671513/
https://www.ncbi.nlm.nih.gov/pubmed/29163464
http://dx.doi.org/10.3389/fimmu.2017.01337