Downregulated IL-21 Response and T Follicular Helper Cell Exhaustion Correlate with Compromised CD8 T Cell Immunity during Chronic Toxoplasmosis

CD8 T cells are important for maintaining the chronicity of Toxoplasma gondii infection. In a T. gondii encephalitis susceptible model, we recently demonstrated that CD4 T cells play an essential helper role in the maintenance of the effector response and CD8 T cell dysfunctionality was linked to CD...

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Detalles Bibliográficos
Autores principales: Moretto, Magali M., Hwang, SuJin, Khan, Imtiaz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671557/
https://www.ncbi.nlm.nih.gov/pubmed/29163509
http://dx.doi.org/10.3389/fimmu.2017.01436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671557/
https://www.ncbi.nlm.nih.gov/pubmed/29163509
http://dx.doi.org/10.3389/fimmu.2017.01436

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