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Generation of an Attenuated Tiantan Vaccinia Virus Strain by Deletion of Multiple Genes

An attenuated vaccinia virus-MVTT(EAB)-was constructed by deletion of non-essential gene segments related to the immunomodulatory and virulence functions of the vaccinia virus Tiantan strain (VVTT). The shuttle plasmids pTC-EGFP, pTE-EGFP, pTA35-EGFP, pTB-EGFP, and pTA66-EGFP were constructed and co...

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Detalles Bibliográficos
Autores principales:	Li, Yiquan, Zhu, Yilong, Chen, Shuang, Li, Wenjie, Yin, Xunzhe, Li, Shanzhi, Xiao, Pengpeng, Han, Jicheng, Li, Xiao, Sun, Lili, Jin, Ningyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671601/ https://www.ncbi.nlm.nih.gov/pubmed/29164070 http://dx.doi.org/10.3389/fcimb.2017.00462

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