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The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications

The insulin receptor (IR) presents by alternative splicing two isoforms: IRA and IRB. The differential physiological and pathological role of both isoforms is not completely known, and it is determinant the different binding affinity for insulin-like growth factor. IRB is more abundant in adult tiss...

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Detalles Bibliográficos
Autores principales:	Escribano, O., Beneit, N., Rubio-Longás, C., López-Pastor, A. R., Gómez-Hernández, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671728/ https://www.ncbi.nlm.nih.gov/pubmed/29201918 http://dx.doi.org/10.1155/2017/1403206

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