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Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice

To evaluate RNA oxidation in the early stage of diabetic nephropathy, we applied an accurate method based on isotope dilution high-performance liquid chromatography-triple quadruple mass spectrometry to analyze the oxidatively generated guanine nucleosides in renal tissue and urine from db/db mice o...

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Detalles Bibliográficos
Autores principales:	Wang, Wan-Xia, Luo, Shun-Bin, Jiang, Ping, Xia, Meng-Ming, Hei, Ai-lian, Mao, Yong-Hui, Li, Chuan-Bao, Hu, Guo-Xin, Cai, Jian-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671745/ https://www.ncbi.nlm.nih.gov/pubmed/29201270 http://dx.doi.org/10.1155/2017/2353729

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