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Leptin Induces Sca-1(+) Progenitor Cell Migration Enhancing Neointimal Lesions in Vessel-Injury Mouse Models
OBJECTIVE—: Leptin is an adipokine initially thought to be a metabolic factor. Recent publications have shown its roles in inflammation and vascular disease, to which Sca-1(+) vascular progenitor cells within the vessel wall may contribute. We sought to elucidate the effects of leptin on Sca-1(+) pr...
Autores principales: | Xie, Yao, Potter, Claire M.F., Le Bras, Alexandra, Nowak, Witold N., Gu, Wenduo, Bhaloo, Shirin Issa, Zhang, Zhongyi, Hu, Yanhua, Zhang, Li, Xu, Qingbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671780/ https://www.ncbi.nlm.nih.gov/pubmed/28935755 http://dx.doi.org/10.1161/ATVBAHA.117.309852 |
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