Cargando…

Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker

BACKGROUND: Preeclampsia is a complex and common human-specific pregnancy syndrome associated with placental pathology. The human specificity provides both intellectual and methodological challenges, lacking a robust model system. Given the role of imprinted genes in human placentation and the vulne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zadora, Julianna, Singh, Manvendra, Herse, Florian, Przybyl, Lukasz, Haase, Nadine, Golic, Michaela, Yung, Hong Wa, Huppertz, Berthold, Cartwright, Judith E., Whitley, Guy, Johnsen, Guro M., Levi, Giovanni, Isbruch, Annette, Schulz, Herbert, Luft, Friedrich C., Müller, Dominik N., Staff, Anne Cathrine, Hurst, Laurence D., Dechend, Ralf, Izsvák, Zsuzsanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671803/ https://www.ncbi.nlm.nih.gov/pubmed/28904069 http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028110

Ejemplares similares

Relaxin Treatment in an Ang-II-Based Transgenic Preeclamptic-Rat Model
por: Haase, Nadine, et al.
Publicado: (2016)

Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner
por: Prokesch, Andreas, et al.
Publicado: (2017)

Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction
por: Nonn, Olivia, et al.
Publicado: (2019)

Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH
por: Singh, Manvendra, et al.
Publicado: (2023)

Relaxin Does Not Improve Angiotensin II-Induced Target-Organ Damage
por: Haase, Nadine, et al.
Publicado: (2014)

Placental Transcriptome Profiling in Subtypes of Diabetic Pregnancies Is Strongly Confounded by Fetal Sex
por: Kedziora, Sarah M., et al.
Publicado: (2022)

Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring—the heart as a target for fetal programming in rats
por: Schütte, Till, et al.
Publicado: (2021)

Continuous Blood Glucose Monitoring Reveals Enormous Circadian Variations in Pregnant Diabetic Rats
por: Golic, Michaela, et al.
Publicado: (2018)

Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes
por: Kräker, Kristin, et al.
Publicado: (2020)

Acute Atherosis Lesions at the Fetal-Maternal Border: Current Knowledge and Implications for Maternal Cardiovascular Health
por: Pitz Jacobsen, Daniel, et al.
Publicado: (2021)

Human Endogenous Retrovirus K Rec Forms a Regulatory Loop with MITF that Opposes the Progression of Melanoma to an Invasive Stage
por: Singh, Manvendra, et al.
Publicado: (2020)

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
por: Langmia, Immaculate M., et al.
Publicado: (2019)

The trophoblast survival capacity in preeclampsia
por: Hutabarat, Martina, et al.
Publicado: (2017)

Decidual cell regulation of trophoblast is altered in pregnancies at risk of pre-eclampsia
por: James-Allan, L B, et al.
Publicado: (2018)

Circular RNA hsa_circ_0081343 promotes trophoblast cell migration and invasion and inhibits trophoblast apoptosis by regulating miR-210-5p/DLX3 axis
por: Wang, Hui, et al.
Publicado: (2021)

The Critical Role of Abnormal Trophoblast Development in the Etiology of Preeclampsia
por: Huppertz, Berthold
Publicado: (2018)

Dlx5 and Dlx6 can antagonize cell division at the G(1)/S checkpoint
por: MacKenzie, Rachel K., et al.
Publicado: (2019)

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation
por: Novakovic, Boris, et al.
Publicado: (2017)

Traditional and New Routes of Trophoblast Invasion and Their Implications for Pregnancy Diseases
por: Huppertz, Berthold
Publicado: (2019)

Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border
por: Narboux-Neme, Nicolas, et al.
Publicado: (2019)

Trophoblast retrieval and isolation from the cervix: origins of cervical trophoblasts and their potential value for risk assessment of ongoing pregnancies
por: Moser, Gerit, et al.
Publicado: (2018)

Inhibition of DDAH1, but not DDAH2, results in apoptosis of a human trophoblast cell line in response to TRAIL
por: Lumicisi, B.A., et al.
Publicado: (2015)

DLX3 interacts with GCM1 and inhibits its transactivation-stimulating activity in a homeodomain-dependent manner in human trophoblast-derived cells
por: Li, Sha, et al.
Publicado: (2017)

DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex
por: Miyano, Masaru, et al.
Publicado: (2008)

Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan
por: de Lombares, Camille, et al.
Publicado: (2019)

DLX Genes: Roles in Development and Cancer
por: Tan, Yinfei, et al.
Publicado: (2021)

Speckle Tracking Echocardiography: New Ways of Translational Approaches in Preeclampsia to Detect Cardiovascular Dysfunction
por: Kräker, Kristin, et al.
Publicado: (2020)

Kidney Injury Caused by Preeclamptic Pregnancy Recovers Postpartum in a Transgenic Rat Model
por: Kedziora, Sarah M., et al.
Publicado: (2021)

Transitory expression of Dlx5 and Dlx6 in maxillary arch epithelial precursors is essential for upper jaw morphogenesis
por: Gitton, Yorick, et al.
Publicado: (2014)

Recurrent purpura due to alcohol-related Schamberg’s disease and its association with serum immunoglobulins: a longitudinal observation of a heavy drinker
por: Bonnet, Udo, et al.
Publicado: (2016)

Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina
por: Zhang, Qi, et al.
Publicado: (2017)

Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants
por: Yung, Hong-wa, et al.
Publicado: (2016)

Early human trophoblast development: from morphology to function
por: Gauster, Martin, et al.
Publicado: (2022)

Downregulation of p53 drives autophagy during human trophoblast differentiation
por: Gauster, Martin, et al.
Publicado: (2017)

DLX, the multiprocessor assembly for LEP/SPS controls
por: Van der Stok, P D V
Publicado: (1990)

Non-parsimonious evolution of hagfish Dlx genes
por: Fujimoto, Satoko, et al.
Publicado: (2013)

Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification
por: Zhu, Hui, et al.
Publicado: (2009)

Loss of dlx5a/dlx6a Locus Alters Non-Canonical Wnt Signaling and Meckel’s Cartilage Morphology
por: Yu, Emily P. Y., et al.
Publicado: (2023)

A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass
por: Singh, Manvendra, et al.
Publicado: (2023)

Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study
por: Kvehaugen, Anne Stine, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_p8e3mol1r6t36g5146qassdrc7