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Jiang Tang Xiao Ke Granule Play an Anti-diabetic Role in Diabetic Mice Pancreatic Tissue by Regulating the mRNAs and MicroRNAs Associated with PI3K-Akt Signaling Pathway

Purpose: To investigate the effect of JTXK granule on the expression pattern of miRNA in pancreatic tissue of KKAy diabetic mice, and to explore the molecular mechanism and pathways of JTXK granule in anti-diabetic effect. Methods: We used high fat diet (HFD) to induce the KKAy diabetic mice and scr...

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Detalles Bibliográficos
Autores principales: Mo, Fang-Fang, An, Tian, Zhang, Zi-Jian, Liu, Yu-Fei, Liu, Hai-Xia, Pan, Yan-Yun, Miao, Jia-Nan, Zhao, Dan-Dan, Yang, Xiu-Yan, Zhang, Dong-Wei, Jiang, Guang-Jian, Gao, Si-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671979/
https://www.ncbi.nlm.nih.gov/pubmed/29163176
http://dx.doi.org/10.3389/fphar.2017.00795