Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads

Synthetic glucocorticoids (GC) are the mainstay therapy for treatment of acute and chronic inflammatory disorders. Due to the high adverse effects associated with long-term use, GC pharmacology has focused since the nineties on more selective GC ligand-binding strategies, classified as selective glu...

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Detalles Bibliográficos
Autores principales: Chirumamilla, Chandra S., Palagani, Ajay, Kamaraj, Balu, Declerck, Ken, Verbeek, Marinus W. C., Oksana, Ryabtsova, De Bosscher, Karolien, Bougarne, Nadia, Ruttens, Bart, Gevaert, Kris, Houtman, René, De Vos, Winnok H., Joossens, Jurgen, Van Der Veken, Pieter, Augustyns, Koen, Van Ostade, Xaveer, Bogaerts, Annemie, De Winter, Hans, Vanden Berghe, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672024/
https://www.ncbi.nlm.nih.gov/pubmed/29163463
http://dx.doi.org/10.3389/fimmu.2017.01324

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