Punica granatum L. Fruit Aqueous Extract Suppresses Reactive Oxygen Species-Mediated p53/p65/miR-145 Expressions followed by Elevated Levels of irs-1 in Alloxan-Diabetic Rats

OBJECTIVE: Reactive oxygen species (ROS) is an apoptosis inducer in pancreatic β-cells that stimulates p53/p65 mediated microRNA (miR)-145 expression. Punica granatum L. (pomegranate) is an antioxidant fruit that attenuates ROS generation. This study examines the effects of pomegranate fruit aqueous...

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Detalles Bibliográficos
Autores principales: Gharib, Ehsan, Kouhsari, Shideh Montasser, Izad, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672089/
https://www.ncbi.nlm.nih.gov/pubmed/29105385
http://dx.doi.org/10.22074/cellj.2018.4550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672089/
https://www.ncbi.nlm.nih.gov/pubmed/29105385
http://dx.doi.org/10.22074/cellj.2018.4550

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