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The Molecular Chaperone Artemin Efficiently Blocks Fibrillization of TAU Protein In Vitro
OBJECTIVE: Aggregation of the TAU proteins in the form of neurofibrillary tangles (NFTs) in the brain is a common risk factor in tauopathies including Alzheimer’s disease (AD). Several strategies have been implemented to target NFTs, among which chaperones, which facilitate the proper folding of pro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royan Institute
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672095/ https://www.ncbi.nlm.nih.gov/pubmed/29105391 http://dx.doi.org/10.22074/cellj.2018.4510 |