Atheroregressive Potential of the Treatment with a Chimeric Monoclonal Antibody against Sulfated Glycosaminoglycans on Pre-existing Lesions in Apolipoprotein E-Deficient Mice

The retention of lipoprotein particles in the intima, in particular to glycosaminoglycan side chains of proteoglycans, is a critical step in atherosclerosis initiation. Administration of chP3R99, a chimeric mouse/human monoclonal antibody inducing an anti-idiotypic network response against glycosami...

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Detalles Bibliográficos
Autores principales: Brito, Victor, Mellal, Katia, Zoccal, Karina F., Soto, Yosdel, Ménard, Liliane, Sarduy, Roger, Faccioli, Lucia H., Ong, Huy, Vázquez, Ana M., Marleau, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672559/
https://www.ncbi.nlm.nih.gov/pubmed/29163168
http://dx.doi.org/10.3389/fphar.2017.00782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672559/
https://www.ncbi.nlm.nih.gov/pubmed/29163168
http://dx.doi.org/10.3389/fphar.2017.00782

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