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Atheroregressive Potential of the Treatment with a Chimeric Monoclonal Antibody against Sulfated Glycosaminoglycans on Pre-existing Lesions in Apolipoprotein E-Deficient Mice
The retention of lipoprotein particles in the intima, in particular to glycosaminoglycan side chains of proteoglycans, is a critical step in atherosclerosis initiation. Administration of chP3R99, a chimeric mouse/human monoclonal antibody inducing an anti-idiotypic network response against glycosami...
Autores principales: | Brito, Victor, Mellal, Katia, Zoccal, Karina F., Soto, Yosdel, Ménard, Liliane, Sarduy, Roger, Faccioli, Lucia H., Ong, Huy, Vázquez, Ana M., Marleau, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672559/ https://www.ncbi.nlm.nih.gov/pubmed/29163168 http://dx.doi.org/10.3389/fphar.2017.00782 |
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