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Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients

OBJECTIVE: To detect subclinical peripheral vascular disease in obese Egyptian patients and establish relations between obesity, metabolic risk factors, and PVD. METHODS: This was a prospective case-control study including 100 obese patients (BMI >30) (G1). In addition, 100 age and sex matched no...

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Autores principales: Younes, Jehan Ahmed, El-Sayed, Nahla Dessoki, Kamel, Ayman Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672746/
https://www.ncbi.nlm.nih.gov/pubmed/29142342
http://dx.doi.org/10.4103/0972-3919.216545
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author Younes, Jehan Ahmed
El-Sayed, Nahla Dessoki
Kamel, Ayman Ismail
author_facet Younes, Jehan Ahmed
El-Sayed, Nahla Dessoki
Kamel, Ayman Ismail
author_sort Younes, Jehan Ahmed
collection PubMed
description OBJECTIVE: To detect subclinical peripheral vascular disease in obese Egyptian patients and establish relations between obesity, metabolic risk factors, and PVD. METHODS: This was a prospective case-control study including 100 obese patients (BMI >30) (G1). In addition, 100 age and sex matched non-obese healthy subjects as a control group (G2). Both groups were subjected to duplex ultrasound, Radionuclide muscle scan. Angiography was done for 17 patients. RESULTS: The image pattern of 99mTc-MIBI muscles uptake was studied and perfusion reserve (PR%) was calculated in (G1) and (G2). Comparison between the two groups showed statistically significant difference (P < 0.001) as regarding laboratory findings. Patients were categorized according to PR% into (+)ve for ischemia (mean PR% was 28.4 ± 20.3) and (-)ve for ischemia (mean PR% was 65.0 ± 11.4). Among (G1) 64 patients positive for ischemia by both PR% and Doppler, 36 patients were negative by Doppler and 22 of them were positive for ischemia by PR%. Angiography was done for 17 of them and proved ischemia in all of them. CONCLUSION: The Tc-99m sestamibi muscle scan can be used as a screening and diagnostic tool of preclinical atherosclerosis in obese patients.
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spelling pubmed-56727462017-11-15 Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients Younes, Jehan Ahmed El-Sayed, Nahla Dessoki Kamel, Ayman Ismail Indian J Nucl Med Original Article OBJECTIVE: To detect subclinical peripheral vascular disease in obese Egyptian patients and establish relations between obesity, metabolic risk factors, and PVD. METHODS: This was a prospective case-control study including 100 obese patients (BMI >30) (G1). In addition, 100 age and sex matched non-obese healthy subjects as a control group (G2). Both groups were subjected to duplex ultrasound, Radionuclide muscle scan. Angiography was done for 17 patients. RESULTS: The image pattern of 99mTc-MIBI muscles uptake was studied and perfusion reserve (PR%) was calculated in (G1) and (G2). Comparison between the two groups showed statistically significant difference (P < 0.001) as regarding laboratory findings. Patients were categorized according to PR% into (+)ve for ischemia (mean PR% was 28.4 ± 20.3) and (-)ve for ischemia (mean PR% was 65.0 ± 11.4). Among (G1) 64 patients positive for ischemia by both PR% and Doppler, 36 patients were negative by Doppler and 22 of them were positive for ischemia by PR%. Angiography was done for 17 of them and proved ischemia in all of them. CONCLUSION: The Tc-99m sestamibi muscle scan can be used as a screening and diagnostic tool of preclinical atherosclerosis in obese patients. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5672746/ /pubmed/29142342 http://dx.doi.org/10.4103/0972-3919.216545 Text en Copyright: © 2017 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Younes, Jehan Ahmed
El-Sayed, Nahla Dessoki
Kamel, Ayman Ismail
Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients
title Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients
title_full Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients
title_fullStr Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients
title_full_unstemmed Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients
title_short Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients
title_sort prevalence of subclinical peripheral vascular disease in obese egyptian patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672746/
https://www.ncbi.nlm.nih.gov/pubmed/29142342
http://dx.doi.org/10.4103/0972-3919.216545
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