Cargando…

Crosstalk between TEMs and endothelial cells modulates angiogenesis and metastasis via IGF1-IGF1R signalling in epithelial ovarian cancer

BACKGROUND: Epithelial ovarian cancer (EOC) is the leading cause of death from gynaecologic malignancies and has a poor prognosis due to metastasis. Drugs targeting the angiogenesis pathway significantly improve patient outcome. However, the key factors linking angiogenesis and metastasis have not b...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xinjing, Zhu, Qinyi, Lin, Yingying, Wu, Li, Wu, Xiaoli, Wang, Kai, He, Qizhi, Xu, Congjian, Wan, Xiaoping, Wang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672923/
https://www.ncbi.nlm.nih.gov/pubmed/28898232
http://dx.doi.org/10.1038/bjc.2017.297