Cargando…

Evaluating the effect of immune cells on the outcome of patients with mesothelioma

BACKGROUND: We systematically assessed the prognostic and predictive value of infiltrating adaptive and innate immune cells in a large cohort of patients with advanced mesothelioma. METHODS: A tissue microarray from 302 samples was constructed. Markers of adaptive immune response in T-cells (CD8(+),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chee, Serena J, Lopez, Maria, Mellows, Toby, Gankande, Sharmali, Moutasim, Karwan A, Harris, Scott, Clarke, James, Vijayanand, Pandurangan, Thomas, Gareth J, Ottensmeier, Christian H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672927/ https://www.ncbi.nlm.nih.gov/pubmed/28817839 http://dx.doi.org/10.1038/bjc.2017.269

Ejemplares similares

Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
por: Ward, M J, et al.
Publicado: (2014)

Crowdsourcing for translational research: analysis of biomarker expression using cancer microarrays
por: Lawson, Jonathan, et al.
Publicado: (2017)

The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma
por: Dalton, L E, et al.
Publicado: (2013)

Overexpression and altered glycosylation of MUC1 in malignant mesothelioma
por: Creaney, J, et al.
Publicado: (2008)

Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4
por: Hanley, Christopher J, et al.
Publicado: (2017)

SV40 associated miRNAs are not detectable in mesotheliomas
por: Gee, G V, et al.
Publicado: (2010)

Markers for the non-invasive diagnosis of mesothelioma: a systematic review
por: van der Bij, S, et al.
Publicado: (2011)

Existing models, but not neutrophil-to-lymphocyte ratio, are prognostic in malignant mesothelioma
por: Meniawy, T M, et al.
Publicado: (2013)

The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma
por: Pinato, D J, et al.
Publicado: (2013)

Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis
por: Kirschner, Michaela B, et al.
Publicado: (2015)

CD74: a new prognostic factor for patients with malignant pleural mesothelioma
por: Otterstrom, C, et al.
Publicado: (2014)

Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells
por: Hoda, M A, et al.
Publicado: (2012)

Secretion of intelectin-1 from malignant pleural mesothelioma into pleural effusion
por: Tsuji, S, et al.
Publicado: (2010)

Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma
por: Ghanim, B, et al.
Publicado: (2014)

Systematic review and meta-analysis of immunohistochemical prognostic biomarkers in resected oesophageal adenocarcinoma
por: McCormick Matthews, L H, et al.
Publicado: (2015)

A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma
por: Kao, Steven C, et al.
Publicado: (2016)

Cisplatin-induced expression of Gb3 enables verotoxin-1 treatment of cisplatin resistance in malignant pleural mesothelioma cells
por: Johansson, D, et al.
Publicado: (2010)

Differential p16/INK4A cyclin-dependent kinase inhibitor expression correlates with chemotherapy efficacy in a cohort of 88 malignant pleural mesothelioma patients
por: Jennings, C J, et al.
Publicado: (2015)

M1(hot) tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer
por: Garrido-Martin, Eva M, et al.
Publicado: (2020)

Co-targeting of FAK and MDM2 triggers additive anti-proliferative effects in mesothelioma via a coordinated reactivation of p53
por: Ou, Wen-Bin, et al.
Publicado: (2016)

FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role
por: Bullock, M D, et al.
Publicado: (2013)

MDM2 is an important prognostic and predictive factor for platin–pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53
por: Walter, R F H, et al.
Publicado: (2015)

Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis
por: Mellone, Massimiliano, et al.
Publicado: (2016)

Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
por: Chua, W, et al.
Publicado: (2011)

Melanoma sentinel node biopsy and prediction models for relapse and overall survival
por: Mitra, A, et al.
Publicado: (2010)

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
por: Ino, Y, et al.
Publicado: (2013)

Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
por: West, N R, et al.
Publicado: (2013)

Expression pattern of tumour-associated antigens in hepatocellular carcinoma: association with immune infiltration and disease progression
por: Liang, J, et al.
Publicado: (2013)

The in situ local immune response, tumour senescence and proliferation in colorectal cancer
por: Roxburgh, C S, et al.
Publicado: (2013)

Arachidonic acid induction of Rho-mediated transendothelial migration in prostate cancer
por: Brown, M, et al.
Publicado: (2014)

FTIR-based spectroscopic analysis in the identification of clinically aggressive prostate cancer
por: Baker, M J, et al.
Publicado: (2008)

VEPH1 expression decreases vascularisation in ovarian cancer xenografts and inhibits VEGFA and IL8 expression through inhibition of AKT activation
por: Shathasivam, Premalatha, et al.
Publicado: (2017)

A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer
por: Proctor, M J, et al.
Publicado: (2012)

Differential radiosensitisation by ZD1839 (Iressa), a highly selective epidermal growth factor receptor tyrosine kinase inhibitor in two related bladder cancer cell lines
por: Maddineni, S B, et al.
Publicado: (2005)

Systemic immune-inflammation index in germ-cell tumours
por: Chovanec, Michal, et al.
Publicado: (2018)

Mapping loss of heterozygosity in normal human breast cells from BRCA1/2 carriers
por: Clarke, C L, et al.
Publicado: (2006)

Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer
por: Ord, J J, et al.
Publicado: (2005)

Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer
por: Chua, W, et al.
Publicado: (2009)

Prognostic impact of tumour-infiltrating immune cells on biliary tract cancer
por: Goeppert, B, et al.
Publicado: (2013)

Active multiple myeloma suppresses and typically eliminates coexisting MGUS
por: Campbell, John P, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i6a69tfbcgeidn8mnu25u7hsjh