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RNA helicase DHX15 acts as a tumour suppressor in glioma

BACKGROUND: Glioblastoma is the most common form of malignant brain cancer and has a poor prognosis in adults. We identified Dhx15 as a candidate tumour suppressor gene in glioma by transposon-based mutagenesis. Dhx15 is an adenosine triphosphate (ATP)-dependent RNA helicase belonging to the DEAH-bo...

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Detalles Bibliográficos
Autores principales:	Ito, Shingo, Koso, Hideto, Sakamoto, Kazuhiro, Watanabe, Sumiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672939/ https://www.ncbi.nlm.nih.gov/pubmed/28829764 http://dx.doi.org/10.1038/bjc.2017.273

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