Cargando…

Scutellarin Inhibits Proliferation, Invasion, and Tumorigenicity in Human Breast Cancer Cells by Regulating HIPPO-YAP Signaling Pathway

BACKGROUND: The present study aimed to investigate the effects of Scutellarin on proliferation, invasion and tumorigenicity in human breast carcinoma MCF-7 cells and its associated molecular mechanisms. MATERIAL/METHODS: The MCF-7 cells were cultured with varies of concentrations of Scutellarin in v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Lengchen, Chen, Lei, Fang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673030/ https://www.ncbi.nlm.nih.gov/pubmed/29079722 http://dx.doi.org/10.12659/MSM.904492

Ejemplares similares

Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells
por: Chai, Yanting, et al.
Publicado: (2018)

Pirfenidone Inhibits Proliferation and Promotes Apoptosis of Hepatocellular Carcinoma Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway
por: Zou, Wei-Jie, et al.
Publicado: (2017)

Long Noncoding RNA LINC003121 Inhibits Proliferation and Invasion of Thyroid Cancer Cells by Suppression of the Phosphatidylinositol-3-Kinase (PI3K)/Akt Signaling Pathway
por: Min, Xiang, et al.
Publicado: (2018)

Curcumin Induces Autophagy via Inhibition of Yes-Associated Protein (YAP) in Human Colon Cancer Cells
por: Zhu, Jing, et al.
Publicado: (2018)

Downregulation of Annexin A11 (ANXA11) Inhibits Cell Proliferation, Invasion, and Migration via the AKT/GSK-3β Pathway in Gastric Cancer
por: Hua, Kelei, et al.
Publicado: (2018)

GANT61 and Valproic Acid Synergistically Inhibited Multiple Myeloma Cell Proliferation via Hedgehog Signaling Pathway
por: Zhang, Zhihua, et al.
Publicado: (2020)

MiR-769 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Targeting HEY1
por: Han, Chao, et al.
Publicado: (2018)

Long Non-Coding RNA TFAP2A-AS1 Inhibits Cell Proliferation and Invasion in Breast Cancer via miR-933/SMAD2
por: Zhou, Bin, et al.
Publicado: (2019)

Partition-Defective 3 (PARD3) Regulates Proliferation, Apoptosis, Migration, and Invasion in Esophageal Squamous Cell Carcinoma Cells
por: Wang, Lei, et al.
Publicado: (2017)

miR-200bc/429 Inhibits Osteosarcoma Cell Proliferation and Invasion by Targeting PMP22
por: Li, Xiaodong, et al.
Publicado: (2017)

Protocadherin 8 (PCDH8) Inhibits Proliferation, Migration, Invasion, and Angiogenesis in Esophageal Squamous Cell Carcinoma
por: Yu, Hong, et al.
Publicado: (2020)

Reciprocal Feedback Loop of the MALAT1-MicroRNA-194-YAP1 Pathway Regulates Progression of Acute Pancreatitis
por: Gu, Lina, et al.
Publicado: (2019)

Anticancer Activity of Phloretin Against Human Gastric Cancer Cell Lines Involves Apoptosis, Cell Cycle Arrest, and Inhibition of Cell Invasion and JNK Signalling Pathway
por: Xu, Min, et al.
Publicado: (2018)

miR-149-5p Inhibits Vascular Smooth Muscle Cells Proliferation, Invasion, and Migration by Targeting Histone Deacetylase 4 (HDAC4)
por: Zhang, Boya, et al.
Publicado: (2019)

Combretastatin A4 Regulates Proliferation, Migration, Invasion, and Apoptosis of Thyroid Cancer Cells via PI3K/Akt Signaling Pathway
por: Liang, Weixin, et al.
Publicado: (2016)

Circular RNA CircMTO1 Inhibits Proliferation of Glioblastoma Cells via miR-92/WWOX Signaling Pathway
por: Zhang, Xuewen, et al.
Publicado: (2019)

Silence of α1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells
por: Zhao, Zhijing, et al.
Publicado: (2018)

The Long Non-Coding RNA MALAT1 Enhances Ovarian Cancer Cell Stemness by Inhibiting YAP Translocation from Nucleus to Cytoplasm
por: Wu, XingMei, et al.
Publicado: (2020)

Long Noncoding RNA HOTTIP Promotes Nasopharyngeal Cancer Cell Proliferation, Migration, and Invasion by Inhibiting miR-4301
por: Shen, Meiqin, et al.
Publicado: (2019)

Circular RNA-0001283 Suppresses Breast Cancer Proliferation and Invasion via MiR-187/HIPK3 Axis
por: Hu, Ying, et al.
Publicado: (2020)

Baicalin Regulates Proliferation, Apoptosis, Migration, and Invasion in Mesothelioma
por: Xu, Wen-Fei, et al.
Publicado: (2019)

Caveolin-1 Inhibits Proliferation, Migration, and Invasion of Human Colorectal Cancer Cells by Suppressing Phosphorylation of Epidermal Growth Factor Receptor
por: Yang, Juanli, et al.
Publicado: (2018)

Verteporfin Promotes the Apoptosis and Inhibits the Proliferation, Migration, and Invasion of Cervical Cancer Cells by Downregulating SULT2B1 Expression
por: Yin, Lijun, et al.
Publicado: (2020)

Xanthoxyletin Inhibits Proliferation of Human Oral Squamous Carcinoma Cells and Induces Apoptosis, Autophagy, and Cell Cycle Arrest by Modulation of the MEK/ERK Signaling Pathway
por: Wen, Qingquan, et al.
Publicado: (2019)

The Effects of Orientin on Proliferation and Apoptosis of T24 Human Bladder Carcinoma Cells Occurs Through the Inhibition of Nuclear Factor-kappaB and the Hedgehog Signaling Pathway
por: Tian, Fenghao, et al.
Publicado: (2019)

The Functional Role of PMP22 Gene in the Proliferation and Invasion of Osteosarcoma
por: Liu, Shuyong, et al.
Publicado: (2015)

Nucleolar and Spindle Associated Protein 1 (NUSAP1) Inhibits Cell Proliferation and Enhances Susceptibility to Epirubicin In Invasive Breast Cancer Cells by Regulating Cyclin D Kinase (CDK1) and DLGAP5 Expression
por: Zhang, Xi, et al.
Publicado: (2018)

Higher Expression of Linc00152 Promotes Bladder Cancer Proliferation and Metastasis by Activating the Wnt/β-Catenin Signaling Pathway
por: Xian-li, Tang, et al.
Publicado: (2019)

Activation of Sonic Hedgehog Signaling Is Associated with Human Osteosarcoma Cells Radioresistance Characterized by Increased Proliferation, Migration, and Invasion
por: Qu, Wei, et al.
Publicado: (2018)

Ras GTPase-Activating-Like Protein IQGAP1 (IQGAP1) Promotes Breast Cancer Proliferation and Invasion and Correlates with Poor Clinical Outcomes
por: Zeng, Fanye, et al.
Publicado: (2018)

C(18)H(17)NO(6) Inhibits Invasion and Migration of Human MNNG Osteosarcoma Cells via the PI3K/AKT Signaling Pathway
por: Qu, Qianqian, et al.
Publicado: (2019)

Knockdown of Phospholipase Cɛ (PLCɛ) Inhibits Cell Proliferation via Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)/AKT Signaling Pathway in Human Prostate Cancer
por: Wang, Xiao, et al.
Publicado: (2018)

WNT974 Inhibits Proliferation, Induces Apoptosis, and Enhances Chemosensitivity to Doxorubicin in Lymphoma Cells by Inhibiting Wnt/β-Catenin Signaling
por: Chen, Senmin, et al.
Publicado: (2020)

Actein Inhibits Cell Proliferation and Migration in Human Osteosarcoma
por: Chen, Zhi, et al.
Publicado: (2016)

Baicalein Enhances Migration and Invasion of Extravillous Trophoblasts via Activation of the NF-κB Pathway
por: Liu, Jia, et al.
Publicado: (2018)

Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway
por: Fang, Kaifeng, et al.
Publicado: (2019)

miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway
por: Yu, Jinzhong, et al.
Publicado: (2017)

Long Noncoding RNA FEZF1-AS1 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer by Activation of JAK-STAT3 Pathway
por: Zhao, Xia, et al.
Publicado: (2018)

Emodin, A Chinese Herbal Medicine, Inhibits Reoxygenation-Induced Injury in Cultured Human Aortic Endothelial Cells by Regulating the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Endothelial Nitric Oxide Synthase (eNOS) Signaling Pathway
por: Shou, Xiaoling, et al.
Publicado: (2018)

Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells
por: Chen, Siwei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_sl3dhfi9g5f9oh21vuth37dn88