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Continuous wound infusion with chloroprocaine in a pig model of surgical lesion: drug absorption and effects on inflammatory response

Continuous wound infusion (CWI) may protect from inflammation, hyperalgesia and persistent pain. Current local anesthetics display suboptimal pharmacokinetic profile during CWI; chloroprocaine (CP) has ideal characteristics, but has never been tested for CWI. We performed an animal study to investig...

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Detalles Bibliográficos
Autores principales:	Allegri, Massimo, Bugada, Dario, De Gregori, Manuela, Avanzini, Maria A, De Silvestri, Annalisa, Petroni, Anna, Sala, Angelo, Filisetti, Claudia, Icaro Cornaglia, Antonia, Cobianchi, Lorenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673045/ https://www.ncbi.nlm.nih.gov/pubmed/29184436 http://dx.doi.org/10.2147/JPR.S139856

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