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Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila

A limited collection of signaling networks and transcriptional effectors directs the full spectrum of cellular behaviors that comprise development. One mechanism to diversify regulatory potential is to combine multiple biochemical activities into the same protein. Exemplifying this principle of modu...

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Detalles Bibliográficos
Autores principales: Davis, Trevor L., Hoi, Charlene S. L., Rebay, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673202/
https://www.ncbi.nlm.nih.gov/pubmed/29108015
http://dx.doi.org/10.1371/journal.pone.0187546

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