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Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom

Numerical simulations are fundamental to the development of medical imaging systems because they can save time and effort in research and development. In this study, we developed a method of creating the virtual projection images that are necessary to study dedicated breast computed tomography (BCT)...

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Autores principales: Jeon, Hosang, Youn, Hanbean, Kim, Jin Sung, Nam, Jiho, Lee, Jayoung, Lee, Juhye, Park, Dahl, Kim, Wontaek, Ki, Yongkan, Kim, Donghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673211/
https://www.ncbi.nlm.nih.gov/pubmed/29108024
http://dx.doi.org/10.1371/journal.pone.0187242
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author Jeon, Hosang
Youn, Hanbean
Kim, Jin Sung
Nam, Jiho
Lee, Jayoung
Lee, Juhye
Park, Dahl
Kim, Wontaek
Ki, Yongkan
Kim, Donghyun
author_facet Jeon, Hosang
Youn, Hanbean
Kim, Jin Sung
Nam, Jiho
Lee, Jayoung
Lee, Juhye
Park, Dahl
Kim, Wontaek
Ki, Yongkan
Kim, Donghyun
author_sort Jeon, Hosang
collection PubMed
description Numerical simulations are fundamental to the development of medical imaging systems because they can save time and effort in research and development. In this study, we developed a method of creating the virtual projection images that are necessary to study dedicated breast computed tomography (BCT) systems. Anthropomorphic software breast phantoms of the conventional compression type were synthesized and redesigned to meet the requirements of dedicated BCT systems. The internal structure of the breast was randomly constructed to develop the proposed phantom, enabling the internal structure of a naturally distributed real breast to be simulated. When using the existing monochromatic photon incidence assumption for projection-image generation, it is not possible to simulate various artifacts caused by the X-ray spectrum, such as the beam hardening effect. Consequently, the system performance could be overestimated. Therefore, we considered the polychromatic spectrum in the projection image generation process and verified the results. The proposed method is expected to be useful for the development and optimization of BCT systems.
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spelling pubmed-56732112017-11-18 Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom Jeon, Hosang Youn, Hanbean Kim, Jin Sung Nam, Jiho Lee, Jayoung Lee, Juhye Park, Dahl Kim, Wontaek Ki, Yongkan Kim, Donghyun PLoS One Research Article Numerical simulations are fundamental to the development of medical imaging systems because they can save time and effort in research and development. In this study, we developed a method of creating the virtual projection images that are necessary to study dedicated breast computed tomography (BCT) systems. Anthropomorphic software breast phantoms of the conventional compression type were synthesized and redesigned to meet the requirements of dedicated BCT systems. The internal structure of the breast was randomly constructed to develop the proposed phantom, enabling the internal structure of a naturally distributed real breast to be simulated. When using the existing monochromatic photon incidence assumption for projection-image generation, it is not possible to simulate various artifacts caused by the X-ray spectrum, such as the beam hardening effect. Consequently, the system performance could be overestimated. Therefore, we considered the polychromatic spectrum in the projection image generation process and verified the results. The proposed method is expected to be useful for the development and optimization of BCT systems. Public Library of Science 2017-11-06 /pmc/articles/PMC5673211/ /pubmed/29108024 http://dx.doi.org/10.1371/journal.pone.0187242 Text en © 2017 Jeon et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Jeon, Hosang
Youn, Hanbean
Kim, Jin Sung
Nam, Jiho
Lee, Jayoung
Lee, Juhye
Park, Dahl
Kim, Wontaek
Ki, Yongkan
Kim, Donghyun
Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
title Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
title_full Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
title_fullStr Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
title_full_unstemmed Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
title_short Generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
title_sort generation of polychromatic projection for dedicated breast computed tomography simulation using anthropomorphic numerical phantom
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673211/
https://www.ncbi.nlm.nih.gov/pubmed/29108024
http://dx.doi.org/10.1371/journal.pone.0187242
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