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NLRP10 Enhances CD4(+) T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10(−/−) mouse to delineate the role of NLRP10 in the host immune response and found that Nlrp10(−/−) dendritic cells (D...

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Detalles Bibliográficos
Autores principales:	Vacca, Maurizio, Böhme, Julia, Zambetti, Lia Paola, Khameneh, Hanif Javanmard, Paleja, Bhairav S., Laudisi, Federica, Ho, Adrian W. S., Neo, Kurt, Leong, Keith Weng Kit, Marzuki, Mardiana, Lee, Bernett, Poidinger, Michael, Santambrogio, Laura, Tsenova, Liana, Zolezzi, Francesca, De Libero, Gennaro, Singhal, Amit, Mortellaro, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673625/ https://www.ncbi.nlm.nih.gov/pubmed/29163529 http://dx.doi.org/10.3389/fimmu.2017.01462

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