Latent HIV-1 TAR Regulates 7SK-responsive P-TEFb Target Genes and Targets Cellular Immune Responses in the Absence of Tat

The transactivating response element (TAR) structure of the nascent HIV-1 transcript is critically involved in the recruitment of inactive positive transcription elongation factor b (P-TEFb) to the promoter proximal paused RNA polymerase II. The viral transactivator Tat is responsible for subsequent...

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Detalles Bibliográficos
Autores principales: Eilebrecht, Sebastian, Benecke, Bernd-Joachim, Benecke, Arndt G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673678/
https://www.ncbi.nlm.nih.gov/pubmed/29037489
http://dx.doi.org/10.1016/j.gpb.2017.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673678/
https://www.ncbi.nlm.nih.gov/pubmed/29037489
http://dx.doi.org/10.1016/j.gpb.2017.05.003

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