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ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair

Global-genome nucleotide excision repair (GG-NER) prevents ultraviolet (UV) light-induced skin cancer by removing mutagenic cyclobutane pyrimidine dimers (CPDs). These lesions are formed abundantly on DNA wrapped around histone octamers in nucleosomes, but a specialized damage sensor known as DDB2 e...

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Detalles Bibliográficos
Autores principales:	Balbo Pogliano, Chiara, Gatti, Marco, Rüthemann, Peter, Garajovà, Zuzana, Penengo, Lorenza, Naegeli, Hanspeter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673894/ https://www.ncbi.nlm.nih.gov/pubmed/29109511 http://dx.doi.org/10.1038/s41467-017-01080-8

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