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Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells
Short chain fatty acids (SCFAs), such as acetate, butyrate and propionate, are products of microbial macronutrients fermentation that distribute systemically and are believed to modulate host immune responses. Recent data have indicated that certain SCFAs, such as butyrate and propionate, directly m...
Autores principales: | Nastasi, Claudia, Fredholm, Simon, Willerslev-Olsen, Andreas, Hansen, Morten, Bonefeld, Charlotte Menné, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels, Woetmann, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673935/ https://www.ncbi.nlm.nih.gov/pubmed/29109552 http://dx.doi.org/10.1038/s41598-017-15099-w |
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