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Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells

Short chain fatty acids (SCFAs), such as acetate, butyrate and propionate, are products of microbial macronutrients fermentation that distribute systemically and are believed to modulate host immune responses. Recent data have indicated that certain SCFAs, such as butyrate and propionate, directly m...

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Detalles Bibliográficos
Autores principales: Nastasi, Claudia, Fredholm, Simon, Willerslev-Olsen, Andreas, Hansen, Morten, Bonefeld, Charlotte Menné, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels, Woetmann, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673935/
https://www.ncbi.nlm.nih.gov/pubmed/29109552
http://dx.doi.org/10.1038/s41598-017-15099-w

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