High-level heterologous production and Functional Secretion by recombinant Pichia pastoris of the shortest proline-rich antibacterial honeybee peptide Apidaecin

Drug resistance is a major problem in antibacterial chemotherapy. Apidaecins, which refer to a series of small, proline-rich antimicrobial peptides, are predominantly active against many drug-resistant bacteria. The apidaecins have special antibacterial mechanisms, and are non-toxic for human cells,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ximing, Li, Juan, Sun, Haili, Li, Shiweng, Chen, Tuo, Liu, Guangxiu, Dyson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674047/
https://www.ncbi.nlm.nih.gov/pubmed/29109421
http://dx.doi.org/10.1038/s41598-017-15149-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674047/
https://www.ncbi.nlm.nih.gov/pubmed/29109421
http://dx.doi.org/10.1038/s41598-017-15149-3

Ejemplares similares