Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation

Cannabidiol (CBD) and ∆(9)-tetrahydrocannabinol (THC) have well documented immunomodulatory effects in vitro, but not following oral administration in humans. Here we show that oral co-administration of cannabinoids with lipids can substantially increase their intestinal lymphatic transport in rats....

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Detalles Bibliográficos
Autores principales: Zgair, Atheer, Lee, Jong Bong, Wong, Jonathan C. M., Taha, Dhiaa A., Aram, Jehan, Di Virgilio, Daisy, McArthur, Joshua W., Cheng, Yu-Kit, Hennig, Ivo M., Barrett, David A., Fischer, Peter M., Constantinescu, Cris S., Gershkovich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674070/
https://www.ncbi.nlm.nih.gov/pubmed/29109461
http://dx.doi.org/10.1038/s41598-017-15026-z

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