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SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

BACKGROUND: Overexpression of epidermal growth factor receptor (EGFR) occurs in approximately 90% of head and neck squamous cell carcinoma (HNSCC), and is correlated with poor prognosis. Thus, targeting EGFR is a promising strategy for treatment of HNSCC. Several small molecule EGFR inhibitors have...

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Detalles Bibliográficos
Autores principales:	Barzegar, Mansoureh, Ma, Shuang, Zhang, Chao, Chen, Xin, Gu, Ying, Shang, Chaowei, Jiang, Xiaojuan, Yang, Jiao, Nathan, Cherie-Ann, Yang, Shengyong, Huang, Shile
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674107/ https://www.ncbi.nlm.nih.gov/pubmed/28873083 http://dx.doi.org/10.1038/bjc.2017.298

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