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A novel function of hepatocyte growth factor in the activation of checkpoint kinase 1 phosphorylation in colon cancer cells

The ATR/checkpoint kinase 1 (Chk1) pathway plays an essential role in modulating the DNA damage response and homologous recombination. Particularly, Chk1 phosphorylation is related to cancer prognosis and therapeutic resistance. Some receptor tyrosine kinases participate in the regulation of Chk1 ph...

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Detalles Bibliográficos
Autores principales:	Song, Na, Che, Xiaofang, Xu, Lu, Qu, Jinglei, Zheng, Huachuan, Hou, Kezuo, Qu, Xiujuan, Liu, Yunpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674134/ https://www.ncbi.nlm.nih.gov/pubmed/28573382 http://dx.doi.org/10.1007/s11010-017-3075-0

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