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Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation

CASE: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non‐prescription weight loss pills containing sibutramine can be still easily purchased over the Internet....

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Autores principales: Bunya, Naofumi, Sawamoto, Keigo, Uemura, Shuji, Kyan, Ryoko, Inoue, Hiroyuki, Nishida, Junichi, Kouzu, Hidemichi, Kokubu, Nobuaki, Miura, Tetsuji, Narimatsu, Eichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674461/
https://www.ncbi.nlm.nih.gov/pubmed/29123885
http://dx.doi.org/10.1002/ams2.275
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author Bunya, Naofumi
Sawamoto, Keigo
Uemura, Shuji
Kyan, Ryoko
Inoue, Hiroyuki
Nishida, Junichi
Kouzu, Hidemichi
Kokubu, Nobuaki
Miura, Tetsuji
Narimatsu, Eichi
author_facet Bunya, Naofumi
Sawamoto, Keigo
Uemura, Shuji
Kyan, Ryoko
Inoue, Hiroyuki
Nishida, Junichi
Kouzu, Hidemichi
Kokubu, Nobuaki
Miura, Tetsuji
Narimatsu, Eichi
author_sort Bunya, Naofumi
collection PubMed
description CASE: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non‐prescription weight loss pills containing sibutramine can be still easily purchased over the Internet. A 21‐year‐old woman without history of cardiovascular diseases developed cardiac arrest. She was a user of a weight loss pills, containing sibutramine and hypokalemia‐inducing agents, imported from Thailand over the Internet. OUTCOME: She was successfully resuscitated without any neurological deficits by using extracorporeal membrane oxygenation for refractory ventricular fibrillation. CONCLUSION: This case indicates that sibutramine can cause cardiac arrest even in subjects without pre‐existing cardiovascular disease when combined with agents that promote QT prolongation.
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spelling pubmed-56744612017-11-09 Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation Bunya, Naofumi Sawamoto, Keigo Uemura, Shuji Kyan, Ryoko Inoue, Hiroyuki Nishida, Junichi Kouzu, Hidemichi Kokubu, Nobuaki Miura, Tetsuji Narimatsu, Eichi Acute Med Surg Case Reports CASE: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non‐prescription weight loss pills containing sibutramine can be still easily purchased over the Internet. A 21‐year‐old woman without history of cardiovascular diseases developed cardiac arrest. She was a user of a weight loss pills, containing sibutramine and hypokalemia‐inducing agents, imported from Thailand over the Internet. OUTCOME: She was successfully resuscitated without any neurological deficits by using extracorporeal membrane oxygenation for refractory ventricular fibrillation. CONCLUSION: This case indicates that sibutramine can cause cardiac arrest even in subjects without pre‐existing cardiovascular disease when combined with agents that promote QT prolongation. John Wiley and Sons Inc. 2017-03-29 /pmc/articles/PMC5674461/ /pubmed/29123885 http://dx.doi.org/10.1002/ams2.275 Text en © 2017 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Bunya, Naofumi
Sawamoto, Keigo
Uemura, Shuji
Kyan, Ryoko
Inoue, Hiroyuki
Nishida, Junichi
Kouzu, Hidemichi
Kokubu, Nobuaki
Miura, Tetsuji
Narimatsu, Eichi
Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
title Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
title_full Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
title_fullStr Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
title_full_unstemmed Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
title_short Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
title_sort cardiac arrest caused by sibutramine obtained over the internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674461/
https://www.ncbi.nlm.nih.gov/pubmed/29123885
http://dx.doi.org/10.1002/ams2.275
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