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Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation
CASE: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non‐prescription weight loss pills containing sibutramine can be still easily purchased over the Internet....
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674461/ https://www.ncbi.nlm.nih.gov/pubmed/29123885 http://dx.doi.org/10.1002/ams2.275 |
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author | Bunya, Naofumi Sawamoto, Keigo Uemura, Shuji Kyan, Ryoko Inoue, Hiroyuki Nishida, Junichi Kouzu, Hidemichi Kokubu, Nobuaki Miura, Tetsuji Narimatsu, Eichi |
author_facet | Bunya, Naofumi Sawamoto, Keigo Uemura, Shuji Kyan, Ryoko Inoue, Hiroyuki Nishida, Junichi Kouzu, Hidemichi Kokubu, Nobuaki Miura, Tetsuji Narimatsu, Eichi |
author_sort | Bunya, Naofumi |
collection | PubMed |
description | CASE: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non‐prescription weight loss pills containing sibutramine can be still easily purchased over the Internet. A 21‐year‐old woman without history of cardiovascular diseases developed cardiac arrest. She was a user of a weight loss pills, containing sibutramine and hypokalemia‐inducing agents, imported from Thailand over the Internet. OUTCOME: She was successfully resuscitated without any neurological deficits by using extracorporeal membrane oxygenation for refractory ventricular fibrillation. CONCLUSION: This case indicates that sibutramine can cause cardiac arrest even in subjects without pre‐existing cardiovascular disease when combined with agents that promote QT prolongation. |
format | Online Article Text |
id | pubmed-5674461 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56744612017-11-09 Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation Bunya, Naofumi Sawamoto, Keigo Uemura, Shuji Kyan, Ryoko Inoue, Hiroyuki Nishida, Junichi Kouzu, Hidemichi Kokubu, Nobuaki Miura, Tetsuji Narimatsu, Eichi Acute Med Surg Case Reports CASE: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non‐prescription weight loss pills containing sibutramine can be still easily purchased over the Internet. A 21‐year‐old woman without history of cardiovascular diseases developed cardiac arrest. She was a user of a weight loss pills, containing sibutramine and hypokalemia‐inducing agents, imported from Thailand over the Internet. OUTCOME: She was successfully resuscitated without any neurological deficits by using extracorporeal membrane oxygenation for refractory ventricular fibrillation. CONCLUSION: This case indicates that sibutramine can cause cardiac arrest even in subjects without pre‐existing cardiovascular disease when combined with agents that promote QT prolongation. John Wiley and Sons Inc. 2017-03-29 /pmc/articles/PMC5674461/ /pubmed/29123885 http://dx.doi.org/10.1002/ams2.275 Text en © 2017 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Bunya, Naofumi Sawamoto, Keigo Uemura, Shuji Kyan, Ryoko Inoue, Hiroyuki Nishida, Junichi Kouzu, Hidemichi Kokubu, Nobuaki Miura, Tetsuji Narimatsu, Eichi Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
title | Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
title_full | Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
title_fullStr | Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
title_full_unstemmed | Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
title_short | Cardiac arrest caused by sibutramine obtained over the Internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
title_sort | cardiac arrest caused by sibutramine obtained over the internet: a case of a young woman without pre‐existing cardiovascular disease successfully resuscitated using extracorporeal membrane oxygenation |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674461/ https://www.ncbi.nlm.nih.gov/pubmed/29123885 http://dx.doi.org/10.1002/ams2.275 |
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