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Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp.
Six new caryophyllene sesquiterpenoids, punctaporonins N–S (1–6), and three known ones, 6-hydroxypunctaporonins B (7), A (8), and E (9), have been isolated from solid cultures of Cytospora sp. The structures of 1–6 were elucidated primarily by NMR spectroscopy. The absolute configuration of 1 was as...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674490/ https://www.ncbi.nlm.nih.gov/pubmed/29204448 http://dx.doi.org/10.1155/2017/7871459 |
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author | Li, Yan Wang, Qingbin Liu, Xingzhong Che, Yongsheng |
author_facet | Li, Yan Wang, Qingbin Liu, Xingzhong Che, Yongsheng |
author_sort | Li, Yan |
collection | PubMed |
description | Six new caryophyllene sesquiterpenoids, punctaporonins N–S (1–6), and three known ones, 6-hydroxypunctaporonins B (7), A (8), and E (9), have been isolated from solid cultures of Cytospora sp. The structures of 1–6 were elucidated primarily by NMR spectroscopy. The absolute configuration of 1 was assigned by X-ray crystallographic analysis of its S-MTPA ester. Compounds 2, 5, and 6 showed modest cytotoxicity against HeLa cells. |
format | Online Article Text |
id | pubmed-5674490 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-56744902017-12-04 Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. Li, Yan Wang, Qingbin Liu, Xingzhong Che, Yongsheng Biomed Res Int Research Article Six new caryophyllene sesquiterpenoids, punctaporonins N–S (1–6), and three known ones, 6-hydroxypunctaporonins B (7), A (8), and E (9), have been isolated from solid cultures of Cytospora sp. The structures of 1–6 were elucidated primarily by NMR spectroscopy. The absolute configuration of 1 was assigned by X-ray crystallographic analysis of its S-MTPA ester. Compounds 2, 5, and 6 showed modest cytotoxicity against HeLa cells. Hindawi 2017 2017-10-24 /pmc/articles/PMC5674490/ /pubmed/29204448 http://dx.doi.org/10.1155/2017/7871459 Text en Copyright © 2017 Yan Li et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Li, Yan Wang, Qingbin Liu, Xingzhong Che, Yongsheng Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. |
title | Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. |
title_full | Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. |
title_fullStr | Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. |
title_full_unstemmed | Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. |
title_short | Punctaporonins N–S, New Caryophyllene Sesquiterpenoids from Cytospora sp. |
title_sort | punctaporonins n–s, new caryophyllene sesquiterpenoids from cytospora sp. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674490/ https://www.ncbi.nlm.nih.gov/pubmed/29204448 http://dx.doi.org/10.1155/2017/7871459 |
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