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Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice

BACKGROUND: TLR ligands can promote Th1-biased immune responses, mimicking potent stimuli of viruses and bacteria. AIM: To investigate the adjuvant properties of dual TLR2/7 ligands compared to those of the mixture of both single ligands. METHODS: Dual TLR2/7 ligands: CL401, CL413, and CL531, includ...

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Detalles Bibliográficos
Autores principales:	Laiño, Jonathan, Wangorsch, Andrea, Blanco, Frank, Wolfheimer, Sonja, Krause, Maren, Flaczyk, Adam, Möller, Tobias-Maximilian, Tsai, Mindy, Galli, Stephen, Vieths, Stefan, Toda, Masako, Scheurer, Stephan, Schülke, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674512/ https://www.ncbi.nlm.nih.gov/pubmed/29204451 http://dx.doi.org/10.1155/2017/7983217

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