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Anesthetic effects on autophagy
Anesthetic agents provide patient comfort and optimize conditions for surgical and procedural interventions. These agents have been shown to modulate autophagy, which is a cellular mechanism that maintains tissue homeostasis by degrading and recycling excess, aged, or dysfunctional proteins. However...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674659/ https://www.ncbi.nlm.nih.gov/pubmed/29152214 http://dx.doi.org/10.4103/2045-9912.215751 |
| _version_ | 1783276819949027328 |
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| author | Ye, Fan Zuo, Zhi-yi |
| author_facet | Ye, Fan Zuo, Zhi-yi |
| author_sort | Ye, Fan |
| collection | PubMed |
| description | Anesthetic agents provide patient comfort and optimize conditions for surgical and procedural interventions. These agents have been shown to modulate autophagy, which is a cellular mechanism that maintains tissue homeostasis by degrading and recycling excess, aged, or dysfunctional proteins. However, it is not always clear if upregulated autophagy is beneficial or harmful. This review assesses the anesthetic effects on autophagy. In the vast majority of studies, anesthetic modulation of autophagy is beneficial for cell survival. |
| format | Online Article Text |
| id | pubmed-5674659 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Medknow Publications & Media Pvt Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-56746592017-11-17 Anesthetic effects on autophagy Ye, Fan Zuo, Zhi-yi Med Gas Res Review Anesthetic agents provide patient comfort and optimize conditions for surgical and procedural interventions. These agents have been shown to modulate autophagy, which is a cellular mechanism that maintains tissue homeostasis by degrading and recycling excess, aged, or dysfunctional proteins. However, it is not always clear if upregulated autophagy is beneficial or harmful. This review assesses the anesthetic effects on autophagy. In the vast majority of studies, anesthetic modulation of autophagy is beneficial for cell survival. Medknow Publications & Media Pvt Ltd 2017-10-17 /pmc/articles/PMC5674659/ /pubmed/29152214 http://dx.doi.org/10.4103/2045-9912.215751 Text en Copyright: © 2017 Medical Gas Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
| spellingShingle | Review Ye, Fan Zuo, Zhi-yi Anesthetic effects on autophagy |
| title | Anesthetic effects on autophagy |
| title_full | Anesthetic effects on autophagy |
| title_fullStr | Anesthetic effects on autophagy |
| title_full_unstemmed | Anesthetic effects on autophagy |
| title_short | Anesthetic effects on autophagy |
| title_sort | anesthetic effects on autophagy |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674659/ https://www.ncbi.nlm.nih.gov/pubmed/29152214 http://dx.doi.org/10.4103/2045-9912.215751 |
| work_keys_str_mv | AT yefan anestheticeffectsonautophagy AT zuozhiyi anestheticeffectsonautophagy |