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Macrophage polarization is related to the pathogenesis of decompression induced lung injury
Studies have shown that blood bubbles may be detectable and there is ultrasonic evidence of acute interstitial lung edema even after diving without protocol violation. Macrophages play a central role in the inflammation, and macrophage polarization is closely related to the pathogenesis some lung di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674661/ https://www.ncbi.nlm.nih.gov/pubmed/29152216 http://dx.doi.org/10.4103/2045-9912.215753 |
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author | Han, Cui-hong Zhang, Pei-xi Liu, Wen-wu |
author_facet | Han, Cui-hong Zhang, Pei-xi Liu, Wen-wu |
author_sort | Han, Cui-hong |
collection | PubMed |
description | Studies have shown that blood bubbles may be detectable and there is ultrasonic evidence of acute interstitial lung edema even after diving without protocol violation. Macrophages play a central role in the inflammation, and macrophage polarization is closely related to the pathogenesis some lung diseases. Available findings indicate that decompression may induce the production of pro-inflammatory cytokines, chemokines, and adhesion molecules in the blood and tissues, which are associated with the macrophage polarization, and hyperbaric treatment may exert therapeutic effects on decompression related diseases via regulating these factors. Thus, we hypothesize that the polarization of circulating and/or resident macrophages is involved in the pathogenesis of decompression induced lung injury. |
format | Online Article Text |
id | pubmed-5674661 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56746612017-11-17 Macrophage polarization is related to the pathogenesis of decompression induced lung injury Han, Cui-hong Zhang, Pei-xi Liu, Wen-wu Med Gas Res Review Studies have shown that blood bubbles may be detectable and there is ultrasonic evidence of acute interstitial lung edema even after diving without protocol violation. Macrophages play a central role in the inflammation, and macrophage polarization is closely related to the pathogenesis some lung diseases. Available findings indicate that decompression may induce the production of pro-inflammatory cytokines, chemokines, and adhesion molecules in the blood and tissues, which are associated with the macrophage polarization, and hyperbaric treatment may exert therapeutic effects on decompression related diseases via regulating these factors. Thus, we hypothesize that the polarization of circulating and/or resident macrophages is involved in the pathogenesis of decompression induced lung injury. Medknow Publications & Media Pvt Ltd 2017-10-17 /pmc/articles/PMC5674661/ /pubmed/29152216 http://dx.doi.org/10.4103/2045-9912.215753 Text en Copyright: © 2017 Medical Gas Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Review Han, Cui-hong Zhang, Pei-xi Liu, Wen-wu Macrophage polarization is related to the pathogenesis of decompression induced lung injury |
title | Macrophage polarization is related to the pathogenesis of decompression induced lung injury |
title_full | Macrophage polarization is related to the pathogenesis of decompression induced lung injury |
title_fullStr | Macrophage polarization is related to the pathogenesis of decompression induced lung injury |
title_full_unstemmed | Macrophage polarization is related to the pathogenesis of decompression induced lung injury |
title_short | Macrophage polarization is related to the pathogenesis of decompression induced lung injury |
title_sort | macrophage polarization is related to the pathogenesis of decompression induced lung injury |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674661/ https://www.ncbi.nlm.nih.gov/pubmed/29152216 http://dx.doi.org/10.4103/2045-9912.215753 |
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