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Case for diagnosis. Systemic light chain amyloidosis with cutaneous involvement

Systemic light chain amiloydosis is a rare disease. Due to its typical cutaneous lesions, dermatologists play an essential role in its diagnosis. Clinical manifestations vary according to the affected organ and are often unspecific. Definitive diagnosis is achieved through biopsy. We report a patien...

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Detalles Bibliográficos
Autores principales: Gontijo, João Renato Vianna, Pinto, Jackson Machado, de Paula, Maysa Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674715/
https://www.ncbi.nlm.nih.gov/pubmed/29166521
http://dx.doi.org/10.1590/abd1806-4841.20176958
Descripción
Sumario:Systemic light chain amiloydosis is a rare disease. Due to its typical cutaneous lesions, dermatologists play an essential role in its diagnosis. Clinical manifestations vary according to the affected organ and are often unspecific. Definitive diagnosis is achieved through biopsy. We report a patient with palpebral amyloidosis, typical bilateral ecchymoses and cardiac involvement, without plasma cell dyscrasia or lymphomas. The patient died shortly after the diagnosis.