Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease

BACKGROUND: Oligodendrocytes (OLs) and myelin are critical for normal brain function and have been implicated in neurodegeneration. Several lines of evidence including neuroimaging and neuropathological data suggest that Alzheimer’s disease (AD) may be associated with dysmyelination and a breakdown...

Descripción completa

Detalles Bibliográficos
Autores principales: McKenzie, Andrew T., Moyon, Sarah, Wang, Minghui, Katsyv, Igor, Song, Won-Min, Zhou, Xianxiao, Dammer, Eric B., Duong, Duc M., Aaker, Joshua, Zhao, Yongzhong, Beckmann, Noam, Wang, Pei, Zhu, Jun, Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Katsel, Pavel, Haroutunian, Vahram, Schadt, Eric E., Popko, Brian, Casaccia, Patrizia, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674813/
https://www.ncbi.nlm.nih.gov/pubmed/29110684
http://dx.doi.org/10.1186/s13024-017-0219-3

Ejemplares similares

Ejemplares similares