Cloning, expression and identification of KTX-Sp4, a selective Kv1.3 peptidic blocker from Scorpiops pococki

BACKGROUND: Specific and selective peptidic blockers of Kv1.3 channels can serve as a valuable drug lead for treating T cell-mediated autoimmune diseases, and scorpion venom is an important source of kv1.3 channel inhibitors. Through conducting transcriptomic sequencing for the venom gland of Scorpi...

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Detalles Bibliográficos
Autores principales: Zou, Yan, Zhang, Feng, Li, Yaxian, Wang, Yuanfang, Li, Yi, Long, Zhengtao, Shi, Shujuan, Shuai, Li, Liu, Jiukai, Di, Zhiyong, Yin, Shijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674823/
https://www.ncbi.nlm.nih.gov/pubmed/29142737
http://dx.doi.org/10.1186/s13578-017-0187-x

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