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Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics
Traditional means for scoring the effects of anti-cancer drugs on the growth and survival of cell lines is based on relative cell number in drug-treated and control samples and is seriously confounded by unequal division rates arising from natural biological variation and differences in culture cond...
Autores principales: | Hafner, Marc, Heiser, Laura M., Williams, Elizabeth H., Niepel, Mario, Wang, Nicholas J., Korkola, James E., Gray, Joe W., Sorger, Peter K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674849/ https://www.ncbi.nlm.nih.gov/pubmed/29112189 http://dx.doi.org/10.1038/sdata.2017.166 |
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