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Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes
Establishing the bipolar spindle in mammalian oocytes after their prolonged arrest is crucial for meiotic fidelity and subsequent development. In contrast to somatic cells, the first meiotic spindle assembles in the absence of centriole-containing centrosomes. Ran-GTP can promote microtubule nucleat...
Autores principales: | Bury, Leah, Coelho, Paula A., Simeone, Angela, Ferries, Samantha, Eyers, Claire E., Eyers, Patrick A., Zernicka-Goetz, Magdalena, Glover, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674873/ https://www.ncbi.nlm.nih.gov/pubmed/28972102 http://dx.doi.org/10.1083/jcb.201606077 |
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