Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin

Cancer-associated fibroblasts (CAFs) are major components of the carcinoma microenvironment that promote tumor progression. However, the mechanisms by which CAFs regulate cancer cell migration are poorly understood. In this study, we show that fibronectin (Fn) assembled by CAFs mediates CAF–cancer c...

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Detalles Bibliográficos
Autores principales: Erdogan, Begum, Ao, Mingfang, White, Lauren M., Means, Anna L., Brewer, Bryson M., Yang, Lijie, Washington, M. Kay, Shi, Chanjuan, Franco, Omar E., Weaver, Alissa M., Hayward, Simon W., Li, Deyu, Webb, Donna J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674895/
https://www.ncbi.nlm.nih.gov/pubmed/29021221
http://dx.doi.org/10.1083/jcb.201704053

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