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Regulation of mitotic spindle assembly factor NuMA by Importin-β
Ran–guanosine triphosphatase orchestrates mitotic spindle assembly by modulation of the interaction between Importin-α/-β and spindle assembly factors (SAFs). The inhibition of SAFs performed by importins needs to be done without much sequestration from abundant nuclear localization signal (NLS) –co...
Autores principales: | Chang, Chih-Chia, Huang, Tzu-Lun, Shimamoto, Yuta, Tsai, Su-Yi, Hsia, Kuo-Chiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674899/ https://www.ncbi.nlm.nih.gov/pubmed/28939615 http://dx.doi.org/10.1083/jcb.201705168 |
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