Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!

Cancer cells thrive on genetic and epigenetic changes that confer a selective advantage but also need strategies to avoid immune recognition. In this issue, Cuellar et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612160) find that the histone methyltransferase SETDB1 enables acute myeloid...

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Detalles Bibliográficos
Autores principales: Robbez-Masson, Luisa, Tie, Christopher H.C., Rowe, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674904/
https://www.ncbi.nlm.nih.gov/pubmed/29066607
http://dx.doi.org/10.1083/jcb.201710068
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author Robbez-Masson, Luisa
Tie, Christopher H.C.
Rowe, Helen M.
author_facet Robbez-Masson, Luisa
Tie, Christopher H.C.
Rowe, Helen M.
author_sort Robbez-Masson, Luisa
collection PubMed
description Cancer cells thrive on genetic and epigenetic changes that confer a selective advantage but also need strategies to avoid immune recognition. In this issue, Cuellar et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612160) find that the histone methyltransferase SETDB1 enables acute myeloid leukemia cells to evade sensing of retrotransposons by innate immune receptors.
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spelling pubmed-56749042018-05-06 Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go! Robbez-Masson, Luisa Tie, Christopher H.C. Rowe, Helen M. J Cell Biol Commentary Cancer cells thrive on genetic and epigenetic changes that confer a selective advantage but also need strategies to avoid immune recognition. In this issue, Cuellar et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612160) find that the histone methyltransferase SETDB1 enables acute myeloid leukemia cells to evade sensing of retrotransposons by innate immune receptors. The Rockefeller University Press 2017-11-06 /pmc/articles/PMC5674904/ /pubmed/29066607 http://dx.doi.org/10.1083/jcb.201710068 Text en © 2017 Robbez-Masson et al. http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Robbez-Masson, Luisa
Tie, Christopher H.C.
Rowe, Helen M.
Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
title Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
title_full Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
title_fullStr Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
title_full_unstemmed Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
title_short Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
title_sort cancer cells, on your histone marks, get setdb1, silence retrotransposons, and go!
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674904/
https://www.ncbi.nlm.nih.gov/pubmed/29066607
http://dx.doi.org/10.1083/jcb.201710068
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