Effects of Histone Deacetylase Inhibitor Panobinostat (LBH589) on Bone Marrow Mononuclear Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms

BACKGROUND: The aim of this study was to explore the impact of LBH589 alone or in combination with proteasome inhibitor bortezomib on multiple myeloma (MM) cell proliferation and its mechanism. MATERIAL/METHODS: MM cell line U266 and RRMM-BMMNC were treated with different concentrations of LBH589 al...

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Detalles Bibliográficos
Autores principales: Ma, Yanping, Liu, Wenhua, Zhang, Ling, Jia, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674922/
https://www.ncbi.nlm.nih.gov/pubmed/29080899
http://dx.doi.org/10.12659/MSM.904232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674922/
https://www.ncbi.nlm.nih.gov/pubmed/29080899
http://dx.doi.org/10.12659/MSM.904232

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