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Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection

Klebsiella pneumoniae is a significant cause of nosocomial pneumonia and an alarming pathogen owing to the recent isolation of multidrug resistant strains. Understanding of immune responses orchestrating K. pneumoniae clearance by the host is of utmost importance. Here we show that type I interferon...

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Detalles Bibliográficos
Autores principales: Ivin, Masa, Dumigan, Amy, de Vasconcelos, Filipe N., Ebner, Florian, Borroni, Martina, Kavirayani, Anoop, Przybyszewska, Kornelia N., Ingram, Rebecca J., Lienenklaus, Stefan, Kalinke, Ulrich, Stoiber, Dagmar, Bengoechea, Jose A., Kovarik, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675380/
https://www.ncbi.nlm.nih.gov/pubmed/29112952
http://dx.doi.org/10.1371/journal.ppat.1006696