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Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis

Carbon-carbon bond formation is one of the most challenging reactions in synthetic organic chemistry, and aldol reactions catalysed by dihydroxyacetone phosphate-dependent aldolases provide a powerful biocatalytic tool for combining C-C bond formation with the generation of two new stereo-centres, w...

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Detalles Bibliográficos
Autores principales: Hartley, Carol J., French, Nigel G., Scoble, Judith A., Williams, Charlotte C., Churches, Quentin I., Frazer, Andrew R., Taylor, Matthew C., Coia, Greg, Simpson, Gregory, Turner, Nicholas J., Scott, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675407/
https://www.ncbi.nlm.nih.gov/pubmed/29112947
http://dx.doi.org/10.1371/journal.pone.0184183