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Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis
Carbon-carbon bond formation is one of the most challenging reactions in synthetic organic chemistry, and aldol reactions catalysed by dihydroxyacetone phosphate-dependent aldolases provide a powerful biocatalytic tool for combining C-C bond formation with the generation of two new stereo-centres, w...
Autores principales: | Hartley, Carol J., French, Nigel G., Scoble, Judith A., Williams, Charlotte C., Churches, Quentin I., Frazer, Andrew R., Taylor, Matthew C., Coia, Greg, Simpson, Gregory, Turner, Nicholas J., Scott, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675407/ https://www.ncbi.nlm.nih.gov/pubmed/29112947 http://dx.doi.org/10.1371/journal.pone.0184183 |
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