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Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model
OBJECTIVE: Systemic sclerosis (SSc) is an autoimmune disease clinically manifesting as progressive fibrosis of the skin and internal organs. Cadherin-11 (CDH11) expression is increased in fibrotic skin and lung tissue. Targeting CDH11 may be an effective approach to treating fibrosis. We hypothesize...
Autores principales: | Pedroza, Mesias, Welschhans, Robert L., Agarwal, Sandeep K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675431/ https://www.ncbi.nlm.nih.gov/pubmed/29112946 http://dx.doi.org/10.1371/journal.pone.0187109 |
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