Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection

Human pegivirus (HPgV) protects HIV+ people from HIV-associated disease, but the mechanism of this protective effect remains poorly understood. We sequentially infected cynomolgus macaques with simian pegivirus (SPgV) and simian immunodeficiency virus (SIV) to model HIV+HPgV co-infection. SPgV had n...

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Detalles Bibliográficos
Autores principales: Bailey, Adam L., Buechler, Connor R., Matson, Daniel R., Peterson, Eric J., Brunner, Kevin G., Mohns, Mariel S., Breitbach, Meghan, Stewart, Laurel M., Ericsen, Adam J., Newman, Christina M., Koenig, Michelle R., Mohr, Emma, Tan, John, Capuano, Saverio, Simmons, Heather A., Yang, David T., O’Connor, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675458/
https://www.ncbi.nlm.nih.gov/pubmed/29073258
http://dx.doi.org/10.1371/journal.ppat.1006692

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