Effective control of acute myeloid leukaemia and acute lymphoblastic leukaemia progression by telomerase specific adoptive T-cell therapy

Telomerase (TERT) is a ribonucleoprotein enzyme that preserves the molecular organization at the ends of eukaryotic chromosomes. Since TERT deregulation is a common step in leukaemia, treatments targeting telomerase might be useful for the therapy of hematologic malignancies. Despite a large spectru...

Descripción completa

Detalles Bibliográficos
Autores principales: Sandri, Sara, De Sanctis, Francesco, Lamolinara, Alessia, Boschi, Federico, Poffe, Ornella, Trovato, Rosalinda, Fiore, Alessandra, Sartori, Sara, Sbarbati, Andrea, Bondanza, Attilio, Cesaro, Simone, Krampera, Mauro, Scupoli, Maria T., Nishimura, Michael I., Iezzi, Manuela, Sartoris, Silvia, Bronte, Vincenzo, Ugel, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675610/
https://www.ncbi.nlm.nih.gov/pubmed/29152058
http://dx.doi.org/10.18632/oncotarget.18115

Ejemplares similares

Ejemplares similares